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Home / Blog / Supplements / Best Digestive Enzymes (2026)

Best Digestive Enzymes (2026)

Helena Kos 01.07.202122.01.2026 Updated22.01.2026

Digestive enzymes are an important part of our digestive system. Without them, the body cannot effectively utilize the nutrients in food, which can lead to digestive disorders and energy deficiencies.

Certain health conditions can interfere with the production of digestive enzymes. In this case, you can add digestive enzymes before meals to help the body process food efficiently.

In this guide, find out which are the most important digestive enzymes, how to recognize their deficiency and which are the best nutritional supplements to support your digestion.

In this article

  • What are digestive enzymes?
    • Where are digestive enzymes secreted?
    • Why is sufficient intake of digestive enzymes important?
    • Natural sources of digestive enzymes
  • What are the best digestive enzymes in dietary supplements?
    • Zona Vital, Enzym 5 Synergy – In the form of capsules
    • Jamieson, Digestive Enzymes – In tablet form
    • Solgar, Digestive Enzymes – In chewable tablet form
    • Caricol, Gastro – In the form of sachets for direct use in the mouth
  • When to use digestive enzymes?
  • Conclusion
  • More product recommendations

What are digestive enzymes?

The digestive system secretes juices that contain enzymes – substances that break down food into its simplest components, and the movements of the digestive system allow for continuous mixing of food and juices, which improves the action of the enzymes.

Digestive enzymes help break down food into a form that can be absorbed in the small intestine. Digestion begins in the mouth, where the first enzyme, ptyalin, is secreted to help break down starch.

Where are digestive enzymes secreted?

Digestive enzymes are substances that break down food into smaller parts that the body can absorb. They are secreted in different parts of the digestive system:

  • Ptyalin – starch breakdown – secreted in the mouth
  • Pepsin – breaks down proteins into amino acids, found in the stomach
  • Amylase – breaks down starch and glycogen, secreted by the pancreas
  • Lipase – breaks down fats, also secreted by the pancreas

Why is sufficient intake of digestive enzymes important?

Lack of digestive enzymes can lead to various gastrointestinal (GI) symptoms. It can also lead to a lack of nutrients even if a person has a healthy diet.

A lack of digestive enzymes can cause:

  • Bloating and gas
  • Diarrhea or constipation
  • Feeling of heaviness and discomfort after eating
  • Lack of fat-soluble vitamins (A, D, E, K)
  • Development of food intolerances

When a person does not have enough of a certain enzyme, food remains undigested or insufficiently digested in the human tract. Insufficiently digested food becomes the perfect medium for the growth of fungi and bacteria, creating a breeding ground for disease.

A lack of the enzyme amylase can lead to diarrhea, a lack of lipase can lead to a deficiency of vitamins A, D, E and K, while a lack of protease can lead to allergies. Enzyme deficiency can also develop various intolerances to certain foods or certain ingredients in food.

Natural sources of digestive enzymes

Certain foods that contain digestive enzymes and can help digestion are: avocado, bananas, ginger, honey, kefir, kiwi, mango, papaya, pineapple, sauerkraut.

What are the best digestive enzymes in dietary supplements?

Zona Vital Enzym 5 Synergy capsules contain a patented, clinically tested multi-enzyme complex with a blend of 5 digestive enzymes. Take 1-2 capsules during or immediately after meals, depending on your needs and your doctor's recommendation.

Zona Vital, Enzym 5 Synergy – In the form of capsules

bell vital enzyme 5Zona Vital, Enzym 5 Synergy, 90 Capsules, 5 Digestive Enzymes

Jamieson digestive enzymes contain a combination of digestive enzymes for the metabolism of proteins, fats, carbohydrates, starches, dairy products and fibers. Take 1 tablet 2 to 3 times a day with a meal.

Jamieson, Digestive Enzymes – In tablet form

Jamieson Nutrisentials Digestive Enzymes, 90 Tablets, For Optimal Digestion FunctioningJamieson, Digestive Enzymes, 90 Tablets, For Optimal Digestive Functioning

Solgar, Digestive Enzymes – In chewable tablet form

Solgar digestive enzymes are in the form of chewable tablets and contain a complex of plant enzymes. Take 1-3 tablets a day with a meal.

Solgar Digestive Enzymes 50 Tablets ChewableSolgar, Digestive Enzymes, 50 Chewable Tablets

Caricol, Gastro – In the form of sachets for direct use in the mouth

Caricol, Gastro is a 100% natural product made from organic papaya and oats. Take 2 sachets daily, 1 sachet before the main meal.

Caricol Gastro 2Caricol® Gastro, 20 Sachets, Gastritis, Stomach Pain, Nausea, Bloating, Bad Breath, Heartburn

When to use digestive enzymes?

  • Take enzymes just before or during meals for best results.
  • Monitor the body's reaction and adjust the dose as needed
  • Before long-term use or if you have chronic conditions, consult a doctor or pharmacist.

Conclusion

Digestive enzymes help in the proper breakdown of food and absorption of nutrients.

When there are not enough digestive enzymes, whether due to health conditions, poor eating habits, or aging, digestive disorders such as bloating, gas, diarrhea, and a feeling of heaviness after eating can occur.

By adjusting your diet and consuming foods naturally rich in enzymes, such as avocado, kiwi, pineapple, papaya, sauerkraut, kefir and other fermented foods, many people can experience improvements.

Before using digestive enzymes, it is advisable to consult a doctor or pharmacist, especially if you have chronic digestive problems, are taking medication, or suspect intolerances. With the right choice of dietary supplements, a balanced diet, and a healthy lifestyle, most people can significantly improve their digestion and feel lighter and less tired.

For more health and nutrition tips, follow our blog and explore our range of digestive supplements.

More product recommendations

Product catalog:

  • Digestive enzymes
  • Probiotics
  • Flatulence
  • Stomach problems
  • Diarrhea
  • Constipation

Continue reading:

The best probiotics for adults

Helena Kos

Helena Kos is a graduate economist, pharmaceutical technician, and certified nutritionist, an expert with a unique combination of knowledge in economics, pharmacy, and nutrition. She is dedicated to transparent information and detailed evaluation of dietary supplements, from analyzing ingredients and their effects to the price-quality ratio. Her goal is to empower readers to make informed decisions about their health by offering verified and practical advice based on science.

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apotekos® | Health care institution (pharmacy) - "Ljekarne Kos" | Headquarters: Vinogradska Street 3G, 44330 Novska, Croatia | Pharmacy/Warehouse: Potočna ulica 64, 44330 Novska, Croatia | OIB: 01062641645 | VAT: HR01062641645 | MBS: 120001897 | The company is registered in the court register of the Commercial Court in Zagreb under number Tt-12/2262-2 | The sale of medical products at a distance has been reported to the Agency for Medicines and Medical Devices - "HALMED.hr".

The information on this website is provided for informational purposes only and does not replace a medical examination or individual advice from a pharmacist. Products on this site are not intended to diagnose, treat or cure any disease. For advice on precautions, possible interactions and side effects, consult your doctor or pharmacist. Product images and descriptions may differ from the actual appearance and information on the packaging due to occasional updates by the manufacturer. Always read the information on the original packaging and, where applicable, the instructions for use before consumption. If you suspect a serious adverse reaction or an emergency, seek medical assistance immediately.

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